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Ventripoint Commends Mazankowski Alberta Heart Institute on their Feasibility Study Finding the VMS+ System Can Obviate the Need for Contrast Agents for LV Volumes and EF





Toronto, Ontario - TheNewswire - August 06, 2019 - Ventripoint Diagnostics Ltd. ("Ventripoint" or the "Company") (TSXV:VPT) (OTC:VPTDF) is pleased to announce that Dr. Windram and his group of researchers at the Mazankowski Alberta Heart Institute in Edmonton have completed a clinical study on the ability of the VMS+ whole-heart analysis system to analyze 2D echocardiograms of left-ventricle (LV) volumes and ejection fractions (LVEF) without the need for intravenous ultrasonographic enhancing agents. This feasibility study concluded: "The use of the Ventripoint knowledge-based-reconstruction technique revealed no significant differences in the measurement of left ventricular volumes or ejection fraction in comparison with contrast echocardiography measurements."

"This study suggests a routine echocardiogram without contrast-enhancing agents is adequate to determine LV function if analyzed using the VMS+," commented Dr. George Adams, CEO of Ventripoint. "We thank the clinical team for their excellent work in providing the first data on this important application."

The study included 26 patients and found no significant difference between the end-diastolic (LVED) and end-systolic (LVES) ventricular volumes for the left ventricle and LVEF between conventional 2D ultrasound using the VMS+ system and contrast-enhanced ultrasound. Two-dimensional contrast echocardiography has been the standard of care for LV volumes and EF assessment by echocardiography in technically-challenging patients, but the use of contrast comes with added cost and the small risk of anaphylactic reaction. This promising data shows the potential use of the VMS+ in patients who require accurate measurements of LV volumes and LVEF and obviates the need for contrast media to obtain a result.

A copy of the presentation can be viewed on the Ventripoint website at:

https://www.ventripoint.com/uploads/3/1/3/9/31398805/ase_2019_determination_of_lv_volume_and_ejection_fraction_with_a_novel_3d_knowledge_based_reconstruction_technique_mazankowski_heart_institute.pdf

Contrast-enhanced echocardiography is warranted on 20% of patients where LV function is required and yet is only used 7% of the time due to technical difficulties (Lindner, J.R., Expert Opinion, posted July 10th, 2017 online at the American College of Cardiology). Contrast echocardiography is increasing in use; however, the procedure requires injecting contrast media into patients. This is uncomfortable, expensive, requires training for intravenous access and takes extra examination time.

The VMS+ is a cost-effective cardiac diagnostic tool measuring whole-heart function in pediatrics and adults with accuracy comparable to MRI. Heart disease is the leading cause of death for both men and women worldwide and having a non-invasive system to obtain volume and ejection fractions for all 4 chambers of the heart is essential for patient care.

About Mazankowski Alberta Heart Institute

The Mazankowski Alberta Heart Institute in Edmonton is a world leader in complex cardiac care and surgery. With a collaborative approach, the team of highly skilled cardiologists, cardiovascular surgeons, cardiac care professionals, researchers and educators are advancing the prevention, detection, treatment and study of cardiovascular disease.

About Ventripoint Diagnostics Ltd.

Ventripoint's technology is a leading Artificial Intelligence (AI) approach known as Knowledge-Based Reconstruction (KBR), used to create applications to monitor heart disease, a leading cause of death worldwide. The VMS+ is the first cost-effective and accurate AI tool for measuring whole heart function using conventional ultrasound. The Company has developed a suite of applications for all major heart diseases and is actively commercializing the approach to improve cardiac care.

For further information please contact:

Dr. George Adams, CEO, Telephone: (519) 803-6937

Email: gadams@ventripoint.com

Forward Looking Statements:

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